تاریخ انتشار : یکشنبه 7 آذر 1400 - 17:45
61 بازدید
کد خبر : 127875

کمبود مواد اولیه مانعی در روند تولید واکسن کووید-۱۹ در جهان

کمبود مواد اولیه مانعی در روند تولید واکسن کووید-۱۹ در جهان

سازمان جهانی بهداشت هشدار داد: کمبود مواد خام اولیه می تواند در روند تولید واکسن کووید-۱۹ در جهان اختلال ایجاد کند. به گزارش ایسنا، سازمان جهانی بهداشت (WHO) هشدار داده است که تقاضای بی سابقه برای تولید واکسن کووید-۱۹ در سراسر جهان منجر به کمبود منابع اصلی از جمله شیشه های ویال، فیلترهای پلاستیکی و

کمبود مواد اولیه مانعی در روند تولید واکسن کووید-۱۹ در جهان

سازمان جهانی بهداشت هشدار داد: کمبود مواد خام اولیه می تواند در روند تولید واکسن کووید-۱۹ در جهان اختلال ایجاد کند.

به گزارش ایسنا، سازمان جهانی بهداشت (WHO) هشدار داده است که تقاضای بی سابقه برای تولید واکسن کووید-۱۹ در سراسر جهان منجر به کمبود منابع اصلی از جمله شیشه های ویال، فیلترهای پلاستیکی و مواد اولیه مورد نیاز برای ساخت آنها شده است.

تدروس آدهانوم دبیر کل سازمان جهانی بهداشت گفت: این کمبود می تواند تولید واکسن کووید-۱۹ را محدود کرده و همچنین منابع لازم برای تولید واکسن های معمول کودکان را با خطر مواجه کند.

در گزارش ارائه شده در نشست موسسه چاتم هاوس لندن با همکاری فدراسیون بین المللی تولیدکنندگان دارویی و دیگر ذینفعان بین المللی آمده است: با هدف تامین تجمعی حدود ۱۴ میلیارد دوز واکسن کووید-۱۹ تا پایان سال ۲۰۲۱ این مساله مشخص شد که بسیاری از مواد اولیه و بسته بندی، مواد مصرفی و تجهیزات با کمبود مواجه هستند دارند در نتیجه چندین تولید کننده واکسن این بیماری، قادر به انجام تعهدات فعلی خود برای تولید واکسن نیستند.

ریچارد هچت، مدیر اجرایی ائتلاف آمادگی‌های نوآورانه برای مقابله با اپیدمی گفته است که تهیه واکسن‌های کووید ۱۹ مستلزم تلاش‌های بیشتر است.

شیشه های ویال یکی از محصولاتی است که با چالش های قابل توجهی مواجه است. ماسه جز اقلام اصلی در تولید شیشه، بتن، آسفالت و حتی سیلیکون است و بنابراین بیشترین ماده اولیه مصرفی بعد از آب محسوب می شود. هرچند بنابر اعلام برنامه محیط زیست سازمان ملل، جهان در مسیر کمبود ماسه قرار دارد.

طبق اعلام برنامه محیط زیست سازمان ملل، هر سال بیش از ۴۰ میلیارد تن ماسه استخراج می شود و میزان جهانی استفاده از ماسه طی دو دهه گذشته سه برابر شده است.

به گزارش ایسنا به نقل از cgtn، همچنین به گفته مدیر اجرایی ائتلاف آمادگی‌های نوآورانه برای مقابله با اپیدمی، فاکتور دیگری که تامین واکسن را با خطر روبرو ساخته، اقدام دولتها در متوقف ساختن صادرات مواد خام است.

انتهای پیام

منبع:ایسنا

برچسب ها :

ناموجود
ارسال نظر شما
مجموع نظرات : 0 در انتظار بررسی : 0 انتشار یافته : ۰
  • نظرات ارسال شده توسط شما، پس از تایید توسط مدیران سایت منتشر خواهد شد.
  • نظراتی که حاوی تهمت یا افترا باشد منتشر نخواهد شد.
  • نظراتی که به غیر از زبان فارسی یا غیر مرتبط با خبر باشد منتشر نخواهد شد.

htthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtthtt